Authors : Manmohan Singhal and Arindam Paul
Abstract: A series of 4-methylphenylsemicarbazone was synthesized and investigated for their antipyretic activity using boiled cow milk induced pyrexia in rabbits. It was observed that the compound 4MS-8 exhibited maximum protection against pyrexia. Hydroxy substitution in aldehydic and acetophenic moiety of 4-methylphenylsemicarbazone derivatives significantly increased antipyretic activity.
Manmohan Singhal and Arindam Paul, 2011. 4-Methylphenylsemicarbazone Derivatives Inhibits Cow Milk Induced Pyrexia in Rabbits. International Journal of Molecular Medicine and Advance Sciences, 7: 16-18.