Authors : M.R. Amin , S.M.A. Khalid , M.O. Alam , M. Mostofa , B. K. Paul and M. Shahiduzzaman
Abstract: The research work was carried out to investigate the effects of Helmex? and Peraclear? against gastro-intestinal nematodiasis in sheep. The effects of Helmex? and Peraclear? on clinical parameter (body weight) and some haematological parameters (TEC, Hb, PCV and TLC) in sheep were also determined in this study. Fifteen sheep were selected from fifty five sheep for this study which was heavily infected with gastro-intestinal nematodes marked by McMaster method. Out of three groups of sheep (each containing 5 sheep), one group was kept as control. Another two groups of sheep received separately Helmex? (albendazole, @ 15mg/kg body weight orally, Renata Limited, Bangladesh) and Peraclear? (fenbendazole, @ 5 mg/kg body weight orally, Techno Drugs Limited, Bangladesh). A significant (p<0.01) reduction of EPG count were found on 7th, 14th, 21st and 28th day of Helmex? (83.61%, 82.35%, 79.73% and 77.25%) treated sheep. Significant (p<0.01) reduction of EPG count were also found on 7th, 14th, 21st and 28th day of Peraclear? (84.41%, 83.77%, 81.74% and 79.53%) treated sheep. The EPG count of untreated control group were significantly (p<0.01) increased about 7.88%, 11.45%, 20.15% and 30.26% on 7th, 14th, 21st and 28th day respectively. The EPG count of untreated control group were significantly (p<0.01) increased about 7.88%, 11.45%, 20.15% and 30.26% on 7th, 14th, 21st and 28th day respectively. After treatment with Helmex? and Peraclear?, total erythrocyte count (TEC), haemoglobin (Hb) content and packed cell volume (PCV) were increased significantly (p<0.01 and p<0.05) in sheep. On the other hand total leukocyte count (TLC) was decreased significantly (p<0.01 and p<0.05) in Helmex? and Peraclear? treated sheep. The body weight was increased significantly (p<0.01 and p<0.05) in Helmex? and Peraclear? treated group. On the other hand body weight was decreased in untreated control group. Helmex? and Peraclear? may be used as a broad spectrum anthelmintic against gastro-intestinal nematodiasis in sheep.
M.R. Amin , S.M.A. Khalid , M.O. Alam , M. Mostofa , B. K. Paul and M. Shahiduzzaman , 2005. Effects of Helmex? and Peraclear? Against Gastro-Intestinal Nematodiasis in Sheep . Journal of Animal and Veterinary Advances, 4: 58-62.