Authors : A.R. Intan-Shameha and A.B.Z. Zuki
Abstract: Pregnancy is associated with dramatic changes in morphological structure of endometrium and leucocytes infiltration within the uterus. The main aim of this study was to evaluate compare the histological structure of uterine mucosal of pregnant and non-pregnant rats. A total of eight healthy Spraque-dawley rats were used in this study. They were divided into two groups; pregnant and non-pregnant groups with 4 rats per group. For the pregnant group, the animals were euthanized at 14 days of gestation period. Uterine samples were taken and processed for histological examination using H&E staining and PAS stain for secretory cell count. Histological structure of the uterine mucosal layer of pregnant and non-pregnant rats was significantly difference. Infiltration of PMN cells was higher in non-pregnant rats than those of pregnant rats, whereas, infiltration of lymphocytes and macrophages were diffusely scattered in pregnant rather than the non-pregnant rats.
Intan-Shameha, A.R., and A.B.Z. Zuki , 2005. Microscopic Evaluation of Uterine Mucosa in Pregnant and Non-pregnant Rats . Journal of Animal and Veterinary Advances, 4: 590-594.