Authors : Serdar Pasa , Nuh Kilic , Abidin Atasoy , Onur O. Derincegoz and Aslihan Karul
Abstract: The objective of this study, was the evaluate sCys-C concentration as a marker of acute renal failure in critically ill dogs. For this purpose, a total of 60 dogs with critically ill were investigated. All cases were selected among critically ill dogs, who were classified into the four groups on the basis of clinical examination, laboratory and radiological and ultrasonographical findings; G1-Control (15 healthy dogs) G2-Multiple trauma (15 dogs); G3-Shock (15 dogs); G4-Urogenital disease (15 dogs). Serum Cys-C was measured by sandwich enzyme immunoassay method using ELISA kit. Serum Cr, sUr and sP concentrations were measured by a photometer using commercially available kits. The mean value of sCys-C was 0.46�0.05 mg L 1, the mean value of sCr was 0.54�0.06 mg dL-1, the mean value of sUr was 13.09�3.92 mg dL-1, the mean value of sP was 3.75�0.24 mg dL-1. The mean value of sCys-C, sCr, sUr and sP values for G1 were statistically different, when compared G3 and G4 (p<0.05). There was no statistical difference between G1 and G2.
Serdar Pasa , Nuh Kilic , Abidin Atasoy , Onur O. Derincegoz and Aslihan Karul , 2008. Serum Cystatin C Concentration as a Marker Acute Renal Dysfunction in Critically Ill Dogs. Journal of Animal and Veterinary Advances, 7: 1410-1412.