Authors : S.B. Oladele , I. Enoch and N.D.G. Ibrahim
Abstract: Experiments were performed to determine changes in Histopathology (HP), Haematocrit (HT), Haemoglobin (HB), Haemagglutination Inhibition (HI) antibody titre and total protein (TP) of Japanese quails (Coturnix coturnix japonica) administered different doses of Newcastle disease virus (NDV) Kudu 113 strain through intramuscular (im) route or per os (po). The values of HT,HB,HI and TP were determined by standard laboratory procedures. The results showed that some of the infected quails developed Newcastle disease (ND) with classical clinical signs and gross lesions of the disease. Histopathological lesions observed include focal necrosis, mononuclear cells infiltration and depletion of lymphoid tissues. There was a reduction in values of HT and HB in the infected quails, when compared with the corresponding mean values obtained in the control group. Following infection of quails with NDV Kudu 113 strain, there was a rise in HI antibody titre from zero to maximum mean antibody titres of log210.56�0.29 and log29.89�0.48 in quails administered 0.3 mL of the virus im and po, respectively on day 7 post infection (pi). There was a slight reduction in TP concentration in all the infected groups, irrespective of the route of administration, when compared with the mean value obtained in the control group. It was concluded that vital body parameters were altered in quails infected with NDV Kudu 113 strain.
S.B. Oladele , I. Enoch and N.D.G. Ibrahim , 2008. Changes in Histopathology, Haematocrit, Haemoglobin, Haemagglutination Inhibition Antibody Titre and Total Protein of Japanese Quails (Coturnix coturnix japonica) Administered Different Doses of Newcastle Disease Virus. Journal of Animal and Veterinary Advances, 7: 418-424.