Journal of Animal and Veterinary Advances

Year: 2012
Volume: 11
Issue: 13
Page No. 2347 - 2351

Effect of Iron Supplement on the Activity of Catalase, SDH and Their MRNA Expression in Rex Rabbit

Authors : Zhao-Qin Zhang, Xiang-Ru Zhao, Jun-Feng Lian, Li-Hui Guan and Hai-Wang Zhang

Abstract: The effect of iron (Fe) supplement on the activity of Catalase (CAT) and Sorbitol Dehydrogenase (SDH) in blood and their mRNA expressions in liver cells of rex rabbits were evaluated. The rabbits were fed with basal diets supplemented with 0, 30, 60, 90, 120, 150 and 200 mg kg-1 (FeSO4H2O), respectively for 60 days. The added Fe significantly increased the activity of CAT and SDH in blood compared to controls (0 mg kg-1) but the amount added had little effect. Adding Fe at 30, 60, 90, 120, 150 and 200 mg kg-1 upregulated CAT gene expression by 45, 58, 67, 64, 61 and 63%, respectively. The corresponding gene upregulation for SDH were 41, 59, 71, 69, 67 and 68%. Fe supplement also increased the average daily weight gain and fresh fur areas. All the measurements reached a plateau around 90-120 mg kg-1 added Fe. The information provides a valuable reference to diet formulation optimization specifically for Rex rabbits.

How to cite this article:

Zhao-Qin Zhang, Xiang-Ru Zhao, Jun-Feng Lian, Li-Hui Guan and Hai-Wang Zhang, 2012. Effect of Iron Supplement on the Activity of Catalase, SDH and Their MRNA Expression in Rex Rabbit. Journal of Animal and Veterinary Advances, 11: 2347-2351.

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