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Journal of Animal and Veterinary Advances
Year: 2012 | Volume: 11 | Issue: 14 | Page No.: 2548-2555
DOI: 10.3923/javaa.2012.2548.2555  
Dietary Supplementation with Recombinant Lactoferrampin-Lactoferricin Improves Growth Performance and Affects Serum Parameters in Piglets
Xiangshan Tang , Andrew A. Fatufe , Yulong Yin , Zhiru Tang , Shengping Wang , Zhiqiang Liu , Xinwu and Tie-Jun Li
 
Abstract: Up to thirty piglets with an average live body weight of 5.9±0.5 kg were challenged using enterotoxigenic Escherichia coli and randomly assigned to three treatment groups fed a corn-soybean meal-based diet containing either no addition (control group), 0.1 g kg-1 of lactoferrampin-lactoferricin (lactoferrampin-lactoferricin group) or 0.1 g kg-1 of chlortetracycline (chlortetracycline group) for 21 days. Compared with the control group, dietary supplementation with lactoferrampin-lactoferricin or chlortetracycline increased the body weight and daily weight gain and decreased the feed to gain ratio, diarrhea rate and serum IgM and IgG levels (p<0.05). The serum levels of IL-1β, IL-6, TNF-α, diamine oxidase and endothelin-1 were not significantly different among all treatment groups (p>0.05). Compared with the control group, dietary supplementation with lactoferrampin-lactoferricin changed the serum concentrations of 10 amino acids (p<0.05); dietary supplementation with chlortetracycline only changed the serum histidine concentration (p<0.05). These results indicate that lactoferrampin-lactoferricin and chlortetracycline have similar effects on piglets weaned at 21 days of age which is expected to have practical applications in the livestock industry.
 
How to cite this article:
Xiangshan Tang, Andrew A. Fatufe, Yulong Yin, Zhiru Tang, Shengping Wang, Zhiqiang Liu, Xinwu and Tie-Jun Li, 2012. Dietary Supplementation with Recombinant Lactoferrampin-Lactoferricin Improves Growth Performance and Affects Serum Parameters in Piglets. Journal of Animal and Veterinary Advances, 11: 2548-2555.
DOI: 10.3923/javaa.2012.2548.2555
URL: http://medwelljournals.com/abstract/?doi=javaa.2012.2548.2555