Authors : Qian Wang, Chunxiang Zhang, Youshe Ren, Wenbin Yue, Liguang Shi and Fulin Lei
Abstract: Selenoprotein P (Sepp1) is a protein of considerable intrigue due to its unusual composition and requirements for its biosynthesis. Most selenoproteins contained a single selenocysteine residue, the human, bovine and rodent selenoprotein P genes encode proteins contained 10±12 selenocysteines. In this study, a full-length cDNA was cloned and characterized from Taihang black goat testes. The full-length of Sepp1 (1511 bp) cDNA contained an open reading frame encoding 347 amino acids. Sequence analysis showed that the predicted Sepp1 amino acids shared high identities with that of other species. The order of Sepp1 mRNA expression levels was: liver>lung>spleen>kidney, heart, testes, caput epididymidis and corpus epididymidis.
Qian Wang, Chunxiang Zhang, Youshe Ren, Wenbin Yue, Liguang Shi and Fulin Lei, 2012. Molecular Structure, Expression Analysis and Functional Characterization of Selenoprotein P (SEPP1) in Goat (Capra hircus). Journal of Animal and Veterinary Advances, 11: 2898-2904.