Authors : A.Capasso , G.Brambilla , M.Ferruzzi , L.Lucibelli , F.Franconi , F.Rondoni , G. Mazzanti , C. Daniele , A.Loizzo and Anna Capasso
Abstract: -agonist drugs are illegally used for auxinic purposes in very high doses. Their accumulation in significant amount in the liver or meat of the treated farm animals is evident. Acute intoxication has also been diagnosed in several countries including Italy. Pressure of the official controls pulsed to synthesise as new compounds to escape analytical screening procedures. Here we have reported two new compounds named "A" and "G4", found in animal feeding. Chemical structure was studied through nuclear magnetic resonance imaging (NMR) and infra-red (IR) spectroscopy. The pharmacodynamic of -1 and -2 adrenergic agonist activity was evaluated on isolated guinea pig atrium and trachea.
A.Capasso , G.Brambilla , M.Ferruzzi , L.Lucibelli , F.Franconi , F.Rondoni , G. Mazzanti , C. Daniele , A.Loizzo and Anna Capasso , 2005. -Agonist Intoxication from Meat Ingestion . Journal of Food Technology, 3: 158-160.