Journal of Animal and Veterinary Advances

Year: 2011
Volume: 10
Issue: 15
Page No. 1947 - 1955

Gene Expression of Metabolizing Enzymes in Beagle Dog Intestine

Authors : Sung-Won Park, Hee Yi, Soo-Min Cho, Kyul Jo, Jin-A Park, Soo-Jean Shin, Hee-Jung Cho, Si-Whan Song, Sang Min Jeong and Ho-Chul Shin

References

Amidon, G.L., P.J. Sinko and D. Fleisher, 1988. Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds. Pharm. Res., 5: 651-654.
CrossRef  |  PubMed  |  

Anzenbacher, P. and E. Anzenbacherova, 2001. Cytochromes P450 and metabolism of xenobiotics. Cell. Mol. Life Sci., 58: 737-747.
CrossRef  |  PubMed  |  

Beaumont, K., 2003. The Importance of Gut Wall Metabolism in Determining Drug Bioavailability. In: Drug Bioavailability: Estimation of Solubility, Permeability and Absorption, Waterbeemd, H.V.D., H Lennernas and P. Artursson (Eds.). Wiley-VCH Verlag, New York, pp: 311-328.

Brown, P.O. and D. Botstein, 1999. Exploring the new world of the genome with DNA microarrays. Nat. Genet., 21: 33-37.
CrossRef  |  

Che, M., D.F. Ortiz and I.M. Arias, 1995. Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na+-nucleoside cotransporter. J. Biol. Chem., 270: 13596-13599.
CrossRef  |  PubMed  |  

Ding, X. and L.S. Kaminsky, 2003. Human extrahepatic cytochromes P450: Function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu. Rev. Pharmacol. Toxicol., 43: 149-173.
CrossRef  |  PubMed  |  

Doherty, M.M. and W.N. Charman, 2002. The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism?. Clin. Pharmacokinet., 41: 235-253.
PubMed  |  

Ebner, T., R.P. Remmel and B. Burchell, 1993. Human bilirubin UDP-glucuronosyltransferase catalyzes the glucuronidation of ethinylestradiol. Mol. Pharmacol., 43: 649-654.
PubMed  |  

Emoto, C., H. Yamazaki, S. Yamasaki, N. Shimada, M. Nakajima and T. Yokoi, 2000. Characterization of cytochrome P450 enzymes involved in drug oxidations in mouse intestinal microsomes. Xenobiotica, 30: 943-953.
PubMed  |  

Fang, H., W. Tong, R. Perkins, L. Shi and H. Hong et al., 2005. Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling. BMC Bioinf., 15: S6-S6.
PubMed  |  

Gibbs, J.P., J.S. Yang and J.T. Slattery, 1998. Comparison of human liver and small intestinal glutathione S-transferase-catalyzed busulfan conjugation in vitro. Drug Metab. Dispos., 26: 52-55.
PubMed  |  

Glatt, H., H. Boeing, C.E. Engelke, L. Ma and A. Kuhlow et al., 2001. Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects. Mutat. Res., 482: 27-40.
CrossRef  |  PubMed  |  

Guillemette, C., 2003. Pharmacogenomics of human UDP-glucuronosyltransferase enzymes. Pharm. J., 3: 136-158.
PubMed  |  

Hochner-Celnikier, D., 1999. Pharmacokinetics of raloxifene and its clinical application. Eur. J. Obstet. Gynecol. Reprod. Biol., 85: 23-29.
PubMed  |  Direct Link  |  

Kaminsky, L.S. and M.J. Fasco, 1991. Small intestinal cytochromes P450. Crit. Rev. Toxicol., 21: 407-422.
CrossRef  |  

Kemp, D.C., P.W. Fan and J.C. Stevens, 2002. Characterization of raloxifene glucuronidation in vitro: Contribution of intestinal metabolism to presystemic clearance. Drug Metab. Dispos., 30: 694-700.
PubMed  |  Direct Link  |  

Khanna, R., C.L. Morton, M.K. Danks and P.M. Potter, 2000. Proficient metabolism of irinotecan by a human intestinal carboxylesterase. Cancer Res., 60: 4725-4728.
PubMed  |  

Landowski, C.P., D. Sun, D.R. Foster, S.S. Menon, J.L. Barnett et al., 2003. Gene expression in the human intestine and correlation with oral valacyclovir pharmacokinetic parameters. J. Pharmacol. Exp. Ther., 306: 778-786.
CrossRef  |  

Lindell, M., M. Lang and H. Lennernas, 2003. Expression of genes encoding for drug metabolising cytochrome P450 enzymes and P-glycoprotein in the rat small intestine; comparison to the liver. Eur. J. Drug Metab. Pharmacokinet, 28: 41-48.
CrossRef  |  

Mizuno, N., T. Niwa, Y. Yotsumoto and Y. Sugiyama, 2003. Impact of drug transporter studies on drug discovery and development. Pharmacol. Rev., 55: 425-461.
PubMed  |  Direct Link  |  

Oh, D.M., P.J. Sinko and G.L. Amidon, 1993. Characterization of the oral absorption of some β-lactams: Effect of the α-amino side chain group. J. Pharm. Sci., 82: 897-900.
CrossRef  |  

Prueksaritanont, T., L.M. Gorham, J.H. Hochman, L.O. Tran and K.P. Vyas, 1996. Comparative studies of drug-metabolizing enzymes in dog, monkey and human small intestines and in CaCO-2 cells. Drug Metab. Dispos., 24: 634-642.
Direct Link  |  

Rushmore, T.H. and A.N. Kong, 2002. Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes. Curr. Drug Metab., 3: 481-490.
CrossRef  |  

Shin, H.C., H.R. Kim, H.J. Cho, H. Yi, S.M. Cho et al., 2009. Comparative gene expression of intestinal metabolizing enzymes. Biopharm. Drug Dispos., 30: 411-421.
CrossRef  |  PubMed  |  Direct Link  |  

Starkey, M.P., T.J. Scase, C.S. Mellersh and S. Murphy, 2005. Dogs really are man's best friend-canine genomics has applications in veterinary and human medicine. Brief Funct. Genomic Proteomic, 4: 112-128.
PubMed  |  Direct Link  |  

Takara, K., N. Ohnishi, S. Horibe and T. Yokoyama, 2003. Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily mRNAS in small intestine. Drug Metab. Dispos., 31: 1235-1239.
CrossRef  |  

Tsuji, A., 2002. Transporter-mediated drug interactions. Drug Metab. Pharmacokinet, 17: 253-274.
CrossRef  |  

Wacher, V.J., J.A. Silverman, Y. Zhang and L.Z. Benet, 1998. Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics. J. Pharm. Sci., 87: 1322-1330.
CrossRef  |  PubMed  |  

Wang, W., J. Jiang, C.E. Ballard and B. Wang, 1999. Prodrug approaches to the improved delivery of peptide drugs. Curr. Pharm. Des., 5: 265-287.
PubMed  |  

Watanabe, Y., M. Nakajima and T. Yokoi, 2002. Troglitazone glucuronidation in human liver and intestine microsomes: High catalytic activity of UGT1A8 and UGT1A10. Drug Metab. Dispos., 30: 1462-1469.
PubMed  |  

Wu, B., J. Wang and M. Wang, 2007. Software development in data analysis and mining for cDNA microarray. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 24: 1394-1397.
PubMed  |  

Zhang, W., T.M.C. Tan and L.Y. Lim, 2007. Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats. Drug Metab. Dispos., 35: 110-115.
CrossRef  |  

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