Journal of Animal and Veterinary Advances

Year: 2011
Volume: 10
Issue: 24
Page No. 3287 - 3292

Evaluation of Wound Healing Activity of Silymarin (Silybum marianum) in Streptozotocin Induced Experimental Diabetes in Rats

Authors : Ali Aliabadi, Alireza Yousefi, Amirashkan Mahjoor and Maryam Farahmand

References

Baynes, J.W. and S.R. Thorpe, 1999. Role of oxidative stress in diabetic complications: A new perspective on an old paradigm. Diabetes, 48: 1-9.
CrossRef  |  Direct Link  |  

Bosisio, E., C. Benelli and O. Pirola, 1992. Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes. Pharmacol. Res., 25: 147-154.
PubMed  |  

Ceriello, A., 2000. Oxidative stress and glycemic regulation. Metabolism, 49: 27-29.
CrossRef  |  PubMed  |  Direct Link  |  

De La Puerta, R., E. Martinez, L. Bravo and M.C. Ahumada, 1996. Effect of silymarin on different acute inflammation models and on leukocyte migration. J. Pharm. Pharmacol., 48: 968-970.
CrossRef  |  Direct Link  |  

Dehmlow, C., J. Erhard and H. de Groot, 1996. Inhibition of Kupffer cell functions as an explanation for the hepatoprotective properties of silibinin. Hepatology, 23: 749-754.
PubMed  |  

Di Girolamo, N., A. Underwood, P.J. McCluskey and D. Wakefield, 1993. Functional activity of plasma fibronectin in patients with diabetes mellitus. Diabetes, 42: 1606-1613.
PubMed  |  Direct Link  |  

Fiebrich, F. and H. Koch, 1979. Silymarin, an inhibitor of prostaglandin synthetase. Cell. Mol. Life Sci., 35: 1550-1552.
CrossRef  |  Direct Link  |  

Goodson, W.H. and T.K. Hunt, 1977. Studies of wound healing in experimental diabetes mellitus. J. Surg. Res., 22: 221-227.
PubMed  |  Direct Link  |  

Gupta, O.P., S. Sing, N. Bani, B.D. Malhotra, S.K. Gupta and B. Handa, 2000. Anti-Inflammatory and anti-arthrithic activities of silymarin acting through inhibition of 5-lipoxygenase. Phytomed., 7: 21-24.
CrossRef  |  Direct Link  |  

Huang, J.S., Y.H. Wang, T.Y. Ling, S.S. Chuang, F.E. Johnson and S.S. Huang, 2002. Synthetic TGF-β antagonist accelerates wound healing and reduces scarring. FASEB J., 16: 1269-1270.
PubMed  |  Direct Link  |  

Jeffcoate, W.J., P. Price and K.G. Harding, 2004. Wound healing and treatments for people with diabetic foot ulcers. Diabetes Metab. Res. Rev., 20: S78-S89.
PubMed  |  

Kang, J.S., Y.J. Jeon, H.M. Kim, S.H. Han and K.H. Yang, 2002. Inhibition of inducible nitric-oxide synthase expression by silymarin in lipopolysaccharide-stimulated macrophages. J. Pharmacol. Exp. Ther., 302: 138-144.
CrossRef  |  

Kittur, S., S. Wilasrusmee, W.A. Pedersen, M.P. Mattson and K. Straube-West et al., 2002. Neurotrophic and neuroprotective effects of milk thistle (Silybum marianum) on neurons in culture. J. Mol. Neurosci., 18: 265-269.
PubMed  |  Direct Link  |  

Kren, V. and D. Walterov, 2005. Silybin and silymarin: New effects and applications. Biomed. Papers, 149: 29-41.
PubMed  |  Direct Link  |  

Li, W.L., H.C. Zheng, J. Bukuru and N. de Kimpe, 2004. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. J. Ethnopharmacol., 92: 1-21.
CrossRef  |  PubMed  |  Direct Link  |  

Mantle, D., M.A. Gok and T.W.J. Lennard, 2001. Adverse drug react. Toxicol. Rev., 20: 89-103.

Maritim, A.C., R.A. Sanders and J.B. Watkins III, 2003. Diabetes, oxidative stress, and antioxidants: A review. J. Biochem. Mol. Toxicol., 17: 24-38.
CrossRef  |  Direct Link  |  

McLennan, S., D.K. Yue and S.M. Twigg, 2006. Molecular aspects of wound healing in diabetes. Primary Intention, 14: 8-13.

Pepping, J., 1999. Milk thistle: Silybum marianum. Am. J. Health Syst. Pharm., 56: 1195-1197.

Rakieten, N., M.L. Rakieten and M.V. Nadkarni, 1963. Studies on the diabetogenic action of streptozotocin (NSC-37917). Cancer Chemother. Rep., 29: 91-98.
PubMed  |  

Saliou, C., B. Rihn, J. Cillard, T. Okamoto and L. Packer, 1998. Selective inhibition of NF-κB activation by flavonoid hepatoprotector silymarin in HepG2. Evidence for different activating pathways. FEBS Lett., 440: 8-12.
CrossRef  |  PubMed  |  Direct Link  |  

Singer, A.J. and R.A.F. Clark, 1999. Cutaneous wound healing. N. Engl. J. Med., 341: 738-746.
CrossRef  |  Direct Link  |  

Soto, C., R. Recoba, H. Barron, C. Alvarez and L. Favari, 2003. Silymarin increases antioxidant enzymes in alloxan-induced diabetes in rat pancreas. Comp. Biochem. Physiol. Part C, 136: 205-212.
CrossRef  |  Direct Link  |  

Wall, S.J., D. Bevan, D.W. Thomas, K.G. Harding, D.R. Edwards and G. Murphy, 2002. Differential expression of matrix metalloproteinases during impaired wound healing of the diabetes mouse. J. Invest. Dermatol., 119: 91-98.
CrossRef  |  PubMed  |  Direct Link  |  

Wall, S.J., M.J. Sampson, N. Levell and G. Murphy, 2003. Elevated matrix metalloproteinase-2 and -3 production from human diabetic dermal fibroblasts. Br. J. Dermatol., 149: 13-16.

Zhao, J., M. Lahiri-Chatterjee, Y. Sharma and R. Agarwal, 2000. Inhibitory effect of a flavonoid antioxidant silymarin on benzoyl peroxide-induced tumor promotion, oxidative stress and inflammatory responses in SENCAR mouse skin. Carcinogenesis, 21: 811-816.
Direct Link  |  

Design and power by Medwell Web Development Team. © Medwell Publishing 2024 All Rights Reserved