Authors : O.A. Adeyeba , Y.O. Adesiji and P.O. Omosigho
Abstract: Diabetic patients comprise a large proportion of our outpatient population and deserve special attention. To determine the prevalence, the clinical characteristics, risk factors, causative organisms and antimicrobial susceptibility of Urinary Tract Infection (UTI) in diabetic patients. Mid-stream urine samples were obtained from a total of 320 patients attending medical outpatient clinic, University College Hospital, Ibadan and apparently healthy volunteers from February to July 2006. Medical records were also reviewed and the patients were divided into two groups according to the presence or absence of diabetes, Patients that were confirmed to be diabetic were included in the study. Out of 320 midstream urine samples examined, 174(54.3%) were diabetic, out of which 37(21%) had significant bacteruria, these include 23(61.9%) females and 14(38.1%) males while in 146 control healthy volunteers only 7(5%) had significant bacteruria, which accounted for 84(58%) of male and 62(42%) of female within the age range of 20-65. Escherichia coli was the predominant bacterial isolate as a causative agent of urinary tract infection in both diabetics and healthy volunteers The antibiotic sensitivity pattern showed that most islolates were sensitive to ofloxaxin, Gentamycin, Nitrofurantoin, Nalixidic acid, Cotrimaxole and Rocephine while they are resistant to tetracyclines, ampicillins, cefuroxime and ceftazidine. The complications of diabetes are of great importance both financially and in terms of mortality and morbidity, because of frequency and severity of UTI in these groups of patients it is recommended that periodic screening of diabetics patients be undertaken to permit early detection and treatment of assymptomatic bacteruria.
O.A. Adeyeba , Y.O. Adesiji and P.O. Omosigho , 2007. Bacterial Urinary Tract Infections in Patients with Diabetes Mellitus . International Journal of Tropical Medicine, 2: 89-92.