Abstract: Chronic lungs disease such relapsed tuberculosis of the lungs could lead to complications that could alter the gross anatomy of a region of the body. Complications have been reported from chronic and relapsed lungs infections such as Mycobateruim tuberculosis when they are not properly managed, Although, the indexed case improved within a short time after admission. The reported case was a rare complicated relapsed lungs tuberculosis. He was a 45 years old businessman who presented with history of chronic cough of 25 years duration with associated hemoptysis, treated in the past for lung tuberculosis. He had clinical features and radiological features of destroyed right lung syndrome with dextro cardia following relapsed tuberculosis with possible superimposed infection. He was managed with category two regimen although did not complete his treatment in this facility. Radiographic complications in the index case were mediastinal shift, gross distortion of the right lung with associated fibrosis, contra-lateral lung emphysema which was noticed to compensating for the destroyed right lung. These findings are strongly consistent with some other reports that artificial/pathologic dextro-cardia can be as a result of relapsed tuberculosis with gross distorted chest region. Therefore, physicians should guide against relapsed tuberculosis by revamping Direct Observe Treatment (DOT) through counseling as well as prevent transmission of multi-drug resistance tuberculosis through proper investigation.