Authors : Cucunawangsih , Veli Sungono and Nata Pratama Hardjo Lugito
Abstract: Dengue is an acute systemic viral infection transmitted by Aedes aegypti mosquitoes that is a public health burden in Indonesia with the increasing number of cases, especially during epidemics. Therefore, this study was investigating the prevalence of dengue infection and their serotype pattern in Tangerang, Indonesia. During 9 months-period (July 2011-March 2012), a prospective study of epidemiological and laboratory test based on rapid screening test for NS-1 antigen and confirmatory DENV has been conducted for these cases. Of the 84 samples, 62/84 (73.8%) show positive in dengue cases and 47/82 (57.3%) positive for DENV. DENV-1 was found to be the most common serotype 19/82 (23.2%) followed by DENV-3 17/82 (20.7%), DENV-2 16/82 (19.5%) and DENV-4 7/82 (8.5%) respectively. Out of 47 confirmed dengue infection there were 10/47 (21.3%) infected by two serotype of dengue viruses. Of these, 8/10 (80%) were proved to be secondary infection. The commonest clinical presentations were fever, nausea/vomiting/abdominal discomfort, myalgia and headache. At the time this study was conducted, Tangerang province, Indonesia had become a dengue endemic area with all four DENV circulates. The dominance of DENV-1 was the highest followed by DENV-3, 2 and 4. The occurrence of multi-serotype dengue viruses had a role in the incidence of concurrent DENV infection cases.
Cucunawangsih , Veli Sungono and Nata Pratama Hardjo Lugito, 2016. Distribution of Dengue Virus Serotype in Tangerang, Indonesia. International Journal of Tropical Medicine, 11: 80-83.