Authors : A. K. Sarkar, M. Ali and A. Rahman
Abstract: A study was undertaken on 30 young cattle (age 6-9) months, body weight 60-120 kg (of both sexes) of Bangladesh Agricultural University, Mymensingh affected naturally with various gastrointesitinal Nematodiasis with a view to evaluating. The therapeutic efficacy of ivenmectin two times. The drug was administered at day ‘0` and 30th. In total 20 cattle were given treatment and 10 left as, control animals. The parameters studied were On the basis of fecal egg reduction, the efficacy was 100%, 100%, 100% and 95.8%, on day ‘0`, 7th, 21st and 30th after first treatment .On 30th post treatment day, the drug was repeated and the efficacy was 100% and 100% on 40th and 60th post treatment day (From Day ‘0`) in the animals of control group the `reduction was 0%. The body weight increased on 30th and 60th day in the treatment was not significant compared with the mean values of control group However there were some increase of body weight in both treatment and control group. The body weight increases were 8.60% and 11.95% in the treatment group and 3.26 and 4.34 in the control group on 30th and 60th day. Therefore the net weight gains in the treatment group were 5.44% (5.44% (8.60-3.26) and 7.91% (11.95-4.34) on those days. The growth or weight gain stimulated by ivermectin treatment although not statistically significant was still encouraging. The Hb increase in the treatment group was significant on (p< 0.05) 60th post treatment day. The PCV, total RBC and WBC and differential counts were almost within normal range in both the groups and there were no much detectable changes in the range and mean values of treatment and control group. The relative values of individual types of cells like lymphocyte, neutrophil, monocyte and basophil were also within normal range in both treatment and control groups. However, the percentage of eosinophil was slightly increased in both group in all study days. In parasitic diseases such increase of eosinophil may some time occur (Soulsby, 1989).
Sarkar, A. K., , M. Ali and A. Rahman , 2005. Efficacy of Ivermectin against GastroIntestinal Nematodes in Calves . Journal of Animal and Veterinary Advances, 4: 329-331.