Authors : M.M.El Tahir , I.B.El Tayeb and S. A.I.Shaddad
Abstract: The effects of the aqueous extract of the leaves of solenostemma argel were examined on the isolated rabbit aortic strip and guinea pig atria. The aqueous extract produced stimulatory effect on isolated rabbit aortic strip and this effect was not blocked by tolazoline. When added to isolated guinea pig atria the extract decreased both the rate and force of contraction and this effect was blocked by calcium chloride, it was concluded that the inhibitory effect my be due to the local anaesthetic activity. There fore the antiarrhythmic activity of solenostemma argel should be investigated.
M.M.El Tahir , I.B.El Tayeb and S. A.I.Shaddad , 2005. The Pharmacological Actions of the Aqueous Extract of the Leaves of Solenostemma argel (Hayne) on Isolated Rabbit Aortic Strip and Guinea Pig Atria . Journal of Animal and Veterinary Advances, 4: 831-834.