Abstract: Pre-weaning data on 466 kits from 109 litters, 280 kits from 78 litters and 261kits from 74 litters at birth, 21 and 28 days of age respectively were collected over 3years (1998- 2001). The litters representing 8 genotypes namely New Zealand white x New Zealand white (NZW x NZW) and Chinchilla x Chinchilla (CHA x CHA) purebreds; and New Zealand white x Chinchilla (NZW x CHA), New Zealand white Dutch belted x New Zealand white Dutch belted (NZWDBD x NZWDBD), New Zealand white x New Zealand white Dutch belted (NZW x NZWDBD), New Zealand white Croel x New Zealand white Croel (NZW CRL x NZW CRL), Chinchilla x New Zealand white Dutch Belted (CHA x NZWDBD) and Chinchilla x New Zealand white Croel (CHA x NZW CRL) crossbreds were assessed for effect of genotype, parity of dam, litter size, sex and season of birth on Individual Kit weight (IKT), Litter Weight (LWT) average Litter Weight (LWT) and Litter Size (LTZ) at birth, 21 and 28 days. The analytical results showed that genotype, litter size, parity, sex and season were important sources of variation for performance characteristics studied. Crossbred NZW x CHA and NZWDBD x NZWDBD individual kit weights at birth and 28 day were comparable (p>0.05). NZW- CHA kits were significantly heavier in ALT at birth and 21 days (p<0.05). NZWDBD x NZWDBD kit weighed more in LWT (P<0.05) and recorded larger litter size (p<0.05) at all ages than other genotypes IKT and ALT consistently in creased with litter size at all ages. All traits considered in this study at various ages were inconsistent with parity. The litters born in wet season maintained superior body weights over dry season litters. The sex mean for IKT at 21 day was significantly different (p<0.05) with females weighing more than males. The results of this study indicate that choice of breeds for commercial production should be based on pre-weaning performance. In addition genotype, litter size, parity, sex and season as important sources of variation should be considered in improvement programme to increase meat yield from rabbit breeds and crosses. Furthermore, this study provides corroborative evidence in support of the adoption of cross breeding in the commercial rabbit industry in the humid tropics.