Journal of Animal and Veterinary Advances

Year: 2007
Volume: 6
Issue: 4
Page No. 586 - 590

Serum Proteins, Thyroid Hormones and Alkaline Phosphatase Concentrationsin Acute Experimental Trypanosoma congolense Infection in Yankasa Sheep Immunomodulated with Levamisole

Authors : M. Bisalla , K.A.N. Esievo , N.D.G. Ibrahim and I.A. Lawal

Abstract: Serum proteins, thyroid hormones and alkaline phosphatase concentrations were measured in Yankasa sheep experimentally infected with T. congolense. Parasitemia occurred in the T. congolense infected sheep immunomodulated with levamisole two days earlier than the infected group without immunodulation.Packed cell volume decreased significantly(p< 0.05) in the infected groups with and without immunomodulation when compared to the controls from the first week of infection up to the end of the experiment. Serum total protein, albumin, Thyroxine (T4) and Triiodothyronine (T3) decreased significantly (p< 0.05) in the infected sheep with and without immunodulation when compared to the controls. Serum Thyrotopin (TSH) and Alkaline Phosphate (AP) did not alter significantly (p>0.05) in the infected sheep with and without immunomodulation when compared to the controls throughout the period of the experiment. In general, levamisole administration did not appear to alter the infection when compared to the infected group without immunomodulation.

How to cite this article:

M. Bisalla , K.A.N. Esievo , N.D.G. Ibrahim and I.A. Lawal , 2007. Serum Proteins, Thyroid Hormones and Alkaline Phosphatase Concentrationsin Acute Experimental Trypanosoma congolense Infection in Yankasa Sheep Immunomodulated with Levamisole . Journal of Animal and Veterinary Advances, 6: 586-590.

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