Authors : A. Hayat , F. Temamogullari and F. Baba
Abstract: The effect of taurolidine on wound healing and thickness of scar tissue in rabbits was investigated and compared to commonly used povidone iodine and sodium chloride. Taurolidine applied wounds showed less adherence and a lesser degree exudate. The contraction in taurolidine gauze-applied wounds to was more apparent than other groups. The granulation tissues on all wounds appeared within postoperative days 3-5. The epithelization on all wound boundaries was seen within postoperative days 5-7. The epithelization on taurolidine applied wounds was completed on postoperative day 12. In conclusion, 2% taurolidine has positive effect on the healing of full thickness skin wounds. It also reduced the thickness of scar tissues and may be alternative to the conventional treatments in rabbit model.
A. Hayat , F. Temamogullari and F. Baba , 2008. Effect of Taurolidine on Thickness of SCAR Tissue in Rabbits. Journal of Animal and Veterinary Advances, 7: 1087-1089.