Authors : Mu Li, Limin Gong, Hui Wu, Liying Zhang, Binru Shang and Yiqiang Chen
Abstract: The residue depletion profile of melamine in pigs exposed to melamine contaminated feed was studied. A total of 56 Landrace x Hampshire x Duroc crossbred pigs weighing 30.6±1.8 kg were blocked by weight and randomly assigned to one of two treatments with ratio of barrow to gilt 1:1 and fed diets supplemented with 30 and 100 mg kg-1 melamine for 42 days. The pigs were housed in pens in groups of seven and each treatment was fed to four pens. One pig from each replicate was slaughtered at 0, 12, 24, 48, 96 and 120 h after withdrawing the melamine contaminated diets and samples of kidney, Longissimus dorsi muscle, plasma and urine were analysed for melamine by liquid chromatography-tandem mass spectrometry. The results indicated that the melamine content was higher in the kidney than that in Longissimus dorsi muscle and plasma. The melamine concentrations in urine were much higher than in tissues and plasma. The depletion of melamine residue in pig tissues is relative rapid, its content in kidney, Longissimus dorsi muscle and plasma at 12 and 24 h after withdrawing melamine contaminated diets decreased by around 50 and 70%, respectively. If a melamine withdraw interval was estimated based on pig kidney residues, it will be 96 h and over 120 h for pigs exposed to 30 and 100 mg kg-1 melamine contaminated diets for 42 days, respectively.
Mu Li, Limin Gong, Hui Wu, Liying Zhang, Binru Shang and Yiqiang Chen, 2010. Residue Depletion of Melamine in Pigs Exposed to Melamine Contaminated Feed. Journal of Animal and Veterinary Advances, 9: 2089-2093.