Authors : Ayse Gul Mutlu and Muzaffer Dukel
Abstract: For a number of years, coenzyme Q was known for its key role in mitochondrial bioenergetics; later studies demonstrated its presence in other subcellular fractions and in plasma and extensively investigated its antioxidant role. Coenzyme Q levels are also affected during aging and neurodegenerative diseases. Very few studies have been carried out to know effects of dietary coenzyme Q in wild type animals. Acetyl-l-carnitine facilitates the uptake of acetyl-CoA into the mitochondria during fatty acid oxidation. Acetylcarnitine supplementation has beneficial effects in elderly animals and humans. In current study, the effects of coenzyme Q10 and acetyl-l-carnitine in antioxidant enzyme activities and protein amounts were investigated. The use of coenzyme Q10 and acetyl-l-carnitine, two important component related with mitochondria as food supplements have similar effects in terms of antioxidant enzyme activities and protein amount of organism.
Ayse Gul Mutlu and Muzaffer Dukel, 2010. Effects of Two Important Components Related with Mitochondria; CoQ10 and Acetyl-l-Carnitine in Antioxidant Enzyme Activities. Journal of Animal and Veterinary Advances, 9: 3109-3113.