Abstract: The Pharmacokinetic characters of cefquinome were studied in camels following single intramuscular administration of 1 mg kg^-1 b.wt. Cefquinome concentrations in serum were determined by microbiological assay using Micrococcus luteus (ATCC 9341) as test organism. After intramuscular administration, the mean peak serum Concentrations (C_max) was 1.23 μg mL^-1 and achieved after (t_max) 4.25 h. The absorption half life (t_l/2(ab)) was 4.35 h and the elimination half-life (t_l/2(el)) was 10.24 h. The Mean Residence Time (MRT) was 16.74 h and area under curve from zero time to infinity (AUC_0-∞) was 20.37 μg/mL/h. The serum concentrations of cefquinome along 24 h post-injection in this study was exceeding the MICs of different susceptible micro-organisms responsible for serious disease problems. These findings indicate the suitability of successful use of this antibiotic in camels. A recommended single daily dose of 1 mg kg^-1 of cefquinome given intramuscularly can achieve quite therapeutic concentrations in serum, that exceeding the minimal inhibitory concentrations against different susceptible pathogens.