Authors : Zhang Shunhua, Zhu Li, Tang Guoqing, Shuai Surong, Bai Lin and Li Xuewei
Abstract: A total of 63 individuals from 10 different pig breeds were utilized to sequence the nucleotide sequence of the porcine myogenin gene in this experiment. The amino acid sequences of the porcine myogenin were deduced from the nucleotide sequences to study the amino acid composition and diversity of the porcine myogenin. The following conclusions can be drawn from the experiment. The porcine myogenin consists of 220 amino acids, all of the 20 conventional amino acids can be found in all detected pig breed populations. Only one nonsynonymous mutation happened in Neijiang pig breed caused the substitution of Arg131→Cys131, the myogenin has completely identical deduced amino acid sequence in all the other pig breeds. That means mutations happen in myogenin gene mainly are synonymous mutation and the myogenin gene is very conservative. The structure of porcine myogenin is very stable. In all the detected pig populations the values of Ka and Ks in myogenin are very small that means the porcine myogenin gene keeps in a nature status does not be influenced by artificial selection.
Zhang Shunhua, Zhu Li, Tang Guoqing, Shuai Surong, Bai Lin and Li Xuewei, 2011. The Amino Acid Composition and Diversity Analysis of the Porcine Myogenin. Journal of Animal and Veterinary Advances, 10: 3118-3122.