Authors : Wang Jun, Deng Chang-Yan , Xiong Yuan-Zhu and Zuo Bo
Abstract: Hexokinase II (HK2) has been demonstrated to play as a key enzyme member in the glycolysis reaction. It catalyzes the conversion glucose to glucose-6-phosphate thus committing glucose to the glycolytic pathway. The objective of this study was to investigate the polymorphism in candidate gene HK2 affectting on meat quality and carcass traits in pigs. The polymorphism (G981A) in intron 10 of porcine HK2 gene which resulting in the changes of restriction site for enzyme Msp I was genotyped in the population of 309 F2 pigs of two Large White x Meishan reference family, result of statistical analysis of variance showed that significant difference between AA and BB was found in meat mar,bling (m. Biceps Femoris, BF) traits. This locus is significantly additive in action; there are significant associations of the detected locus between AA and BB were found with loin eye height, average skin thickness and significantly additive in action.
Wang Jun, Deng Chang-Yan , Xiong Yuan-Zhu and Zuo Bo , 2012. Association Analysis of Polymorphism in Intron-10 of Porcine HK2 Gene with Meat Quality and Carcass Traits. Journal of Animal and Veterinary Advances, 11: 1158-1161.