Journal of Animal and Veterinary Advances

Year: 2012
Volume: 11
Issue: 3
Page No. 343 - 345

Polymorphism of Ovar-DRB1 Second Exon with PCR-RFLP Technique in Arabi Sheep Population of Khuzestan Province

Authors : Mojtaba Lotfi, Mohammad Taghi Beigi Nassiri, Hedayatollah Roshanfekr and Jamal Fayazi

Abstract: Major Histocompatibility Complex (MHC) plays a pivotal role in antigen presentation for eliciting immune responses against invading pathogens. The best-characterized genetic control of disease resistance and immune response in animals are associated with MHC. Therefore in this study polymorphism of ovar-DRB1 in DNA samples of 111 heads Arabi sheep using Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) method was examined. Identities of 18 different patterns and 8 distinct DRB1 alleles among Arabi sheep have been determined. There is not deviation in Ovar-DRB1 gene from Hardy-Weinberg equilibrium in this population results showed. Obtained results have revealed that the exon 2 region of ovar-DRB1 was highly polymorphic on Arabi sheep.

How to cite this article:

Mojtaba Lotfi, Mohammad Taghi Beigi Nassiri, Hedayatollah Roshanfekr and Jamal Fayazi, 2012. Polymorphism of Ovar-DRB1 Second Exon with PCR-RFLP Technique in Arabi Sheep Population of Khuzestan Province. Journal of Animal and Veterinary Advances, 11: 343-345.

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