Abstract: Antioxidant activity of Aspirin Eugenol Ester (AEE) for aging model of mice by D-galactose for 8 weeks was investigated. MDA and lipofuscin contents of mice serum and heart, liver were selected as indexes to reflect antioxidant activity. The results showed that the small doses of AEE can effectively remove free radicals caused by D-galactose and large doses of AEE can make free radicals level below the normal level. There were some relationships between dose and effect. Compared with precursor drug aspirin and eugenol, AEE also has stronger antioxidant activity.
Jianyong Li, Yuanguang Yu, Yajun Yang, Xiwang Liu, Jiyu Zhang, Bing Li, Xuzheng Zhou, Jianrong Niu and Xiaojuan Wei, 2012. Antioxidant Activity of Aspirin Eugenol Ester for Aging Model of Mice by D-Galactose. Journal of Animal and Veterinary Advances, 11: 4401-4405.