Authors : Feiyan Dai, Wengui Li, Libo Gao, Gefen Yin, Gang Feng, Weibing Bai and Gang Duan
Abstract: The ORF2 genes of 10 isolated Porcine Circovirus type 2 (PCV2) strains in Yunnan Province of China were sequenced, analyzed and further compared with the sequences of 24 strains retrieved from GenBank. The results showed that the ORF2 genes of the 10 strains in Yunnan Province shared sequence identity of 98.7-100.0% on nucleotide acid level and of 96.2-100.0% on amino acid level. Moreover, Yunnan strains and the other 24 strains retrieved from GenBank shared 91.0-99.7% nucleotide and 80.3-97.4% amino acid sequence similarity. Based on the phylogenetic tree analysis, these strains could be divided into five genotypes (PCV2a-PCV2e) and all the Yunnan strains fall into PCV2b genotype. Compared with other PCV2b strains, nine point mutations of amino acid residues were identified only in Yunnan strains which might be essential for controlling PCV2 infection in Yunnan Province, China.
Feiyan Dai, Wengui Li, Libo Gao, Gefen Yin, Gang Feng, Weibing Bai and Gang Duan, 2013. Phylogenetic Analysis of the ORF2 Genes of Porcine Circovirus 2 Strains Isolated in Yunnan Province, China. Journal of Animal and Veterinary Advances, 12: 1-5.