Journal of Animal and Veterinary Advances

Year: 2013
Volume: 12
Issue: 22
Page No. 1628 - 1631

Effects of Selenium Overexposure on Glutathione Peroxidase and Selenoprotein W Gene Expression in the Jejunum

Authors : Qin Zhang, Bitao Liu, Liangyan Zheng and Zhaoxin Tang

Abstract: Researchers determined how oxidative stress induced by excess Se alters expression of selected selenoproteins in the jejunum from mice fed diets of different Se content. Deficient Se diet downregulated the mRNA level of GPx1, GPx4 and SEPW1; super nutrition Se dramatically increased the level of GPx1 and SEPW1 mRNA levels but had no effect on GPx2 mRNA level. The excess Se diet led to decrease GPx1 and SEPW1 mRNA levels but had little effect on the level of GPx4 mRNA. The data show that mRNA levels of the GPx family or selenoprotein W are differentially regulated by dietary Se.

How to cite this article:

Qin Zhang, Bitao Liu, Liangyan Zheng and Zhaoxin Tang, 2013. Effects of Selenium Overexposure on Glutathione Peroxidase and Selenoprotein W Gene Expression in the Jejunum. Journal of Animal and Veterinary Advances, 12: 1628-1631.

Design and power by Medwell Web Development Team. © Medwell Publishing 2022 All Rights Reserved