Authors : Chunyang Jia, Zongsheng Zhao, Hailong Hu, Yanjun Mu, Zhimian Li and Qingfeng Li
Abstract: The abundance of GHR (Growth Hormone Receptor) expression and the expression spot in the sheep skin were researched by using relative quota RT-PCR and the organization in situ hybridization. The mRNA level of GHR in the epilated group skin obviously went down in 0th-3rd days and rose to the level before the epilating again in the 6th day. There were not obvious changes in the later. Compared with the control group there was no obvious changes. Though, GHR mRNA in the epilated group obviously was lower than the control group in the 3rd day. But the hybridization signal demonstrated that the closest spot is hair-follicle’s wool nipple and exterior and interior root-sheath on the cut sheet. The dermis and various kinds of different cuticle cells have the very weak hybrid signal or not have. GHR has effect on the hair-follicle cell and it is possibly related to the wool character regulation.
Chunyang Jia, Zongsheng Zhao, Hailong Hu, Yanjun Mu, Zhimian Li and Qingfeng Li, 2014. GHR in Sheep Skin’s Localization and Related Function Research. Journal of Animal and Veterinary Advances, 13: 416-422.