Authors : Chen-Chen Wu, Baoyu Zhao, XiaoBing Li, GuoWen Liu and Zhe Wang
Abstract: Pseudopurpurin improves bone strength, structure and metabolic function in 18 months old red-boned goats in previous experiment. The objective of the study was to evaluate whether the greater pseudopurpurin deposition would result in better bone mechanical properties, geometry and architecture in red-boned goats with age. Bone mineral density, geometry, architecture and mechanical properties were analyzed using dual-energy X-ray absorptiometry, micro-computed tomography and materials-testing. The results showed that bone mineral densities, the micro-structural parameters and mechanical properties of the distal femur and femoral diaphysis in red-boned goats were not significantly different from common goats at 6 months of age. At 12 months of age, the micro-structural parameters and mechanical properties of the distal femur were better in red-boned than in common goats, the marrow area, cortical area and total area of the femoral diaphysis in red-boned goats were significantly different from common goats. The findings suggest that the pseudopurpurin was initially deposited in the cancellous bone and then in the cortical bone of the red-boned goats thus, the changes in bone parameters were seen earlier in the cancellous bone than the cortical bone. Both the pseudopurpurin deposit and the geometry and strength of the femur increased with age in red-boned goats.
Chen-Chen Wu, Baoyu Zhao, XiaoBing Li, GuoWen Liu and Zhe Wang, 2014. Changes in Bone Mechanical Properties and Geometry are Associated with Age and Pseudopurpurin Deposition in Red-Boned Guishan Goats. Journal of Animal and Veterinary Advances, 13: 66-71.