Abstract: Harmful products are sometime being marketed to the consumers by manufacturers and their distributors most especially the wholesalers and the retailers. The consequences of this phenomenon has made it imperative for government and private sector to employ de-marketing strategy to address this situation. The objective of this study therefore is to examine the major problems facing these de-marketing strategies being employed by both the government and private sector and proffer the needed solutions to these problems. In other word, the objective of this study is to examine how de-marketing tools have been effectively used against consumption of harmful products in Nigeria. The t-test and Chi-square were the statistical techniques employed to test the hypotheses raised in the study. The results of the findings indicated that the de-marketing strategy has been effective while inadequate legislation serve as one of the major problems facing this policy. The study recommends that a stiffer penalty in form of capital punishment or life imprisonment should be imposed on offenders who are involved in production and sales of harmful products so as to serve as deterrent to others.