Abstract: Bactericidal and fungicidal were carried out on Cu(II) and Ni(II) paramethoxy and parahydroxy benzoic acid hydrazides activities of the synthesized compounds were screened against 12 microorganisms viz: Yersinia sp., Klebsilla sp., Saccharomyces cerevisae, Candida albicans, Rhodosporium sp., Proteus vulgaris, Staphylococcus aureus and E. coli. The biological properties of the metal complexes revealed that in general complexation led to enhanced activity. The Cu(II) complexes appears to be much more potent antibacterial agents that the Ni(II) complexes in vitro; the three fungi used in this research Rhodosporum sp., Saccharoymces cerevisae and Candida sp. are completely resistant to all the copper complexes. They are susceptible to at least one of the nickel complexes. E. coli and P. vulgaris are completely resistant to the nickel complexes.
I.O. Adeoye , O.O. Adelowo , M.A Oladipo and O.A. Odunola , 2007. Comparison of Bactericidal and Fungicidal Activities of Cu (Ii) and Ni (Ii) Complexes of Para-Methoxy and Para-Hydroxy Benzoic Acid Hydrazide . Research Journal of Applied Sciences, 2: 590-594.