Abstract: The studies carried out on the basis of the Caucasus Mountains, support the concept of modern denudation multifactorial processes. As might be expected, the presence or absence of links between the rate of denudation and natural anthropogenic factors, determining these rates, depends mainly on the degree of data detail concerning the spatial variability of different factors. The results suggest that the Caucasus region has a reliable set of data that allowed to establish certain relationship between the individual factors and denudation rates for each of the high-altitude zones. In terms of Caucasus among all factors the greatest impact on the Annual Layer Flush index, characterizing the total removal of loose fragmental material beyond the River Basin is performed by lithology and terrain elevation. The contribution of other factors such as slope and slope exposures, water reserves in a snow cover, the layer of atmospheric precipitation, temperature fluctuations, forest coverage, soil type and population density is clearly manifested only in certain regions.