Abstract: This descriptive-correlational study was conducted to compare organizational commitment, life expectancy and mental health of nurses and ordinary people in Zabol. To this end, 168 nurses (105 females and 63 males) and 168 ordinary individuals (68 females and 100 males) were selected through applying random sampling method. In the current study, three questionnaires including General Health Questionnaire (GHO-28), Life Expectancy Scale and Organizational Commitment Questionnaire were used to collect data. Moreover, subjects’ demographic information was also obtained. The collected data was statistically analyzed using Pearson correlation coefficient and independent t-test. Results of the present study indicated that there was a diverse significant relationship between scores on mental health and life expectancy. However, no significant relationship was found between mental health and organizational commitment of nurses in Zabol. Moreover, no significant correlation was observed among mental health, life expectancy and organizational commitment of ordinary people in Zabol. There was a significant difference between nurses and ordinary people considering their organizational commitment, i.e., mean score of ordinary people on organizational commitment was higher than that of nurses, demonstrating that ordinary people were more committed to their work. Additionally, there was a significant difference between nurses and ordinary people with regard to their mental health, i.e., ordinary people’s mean score on mental health was lower than that of nurses, indicating that nurses had higher levels of mental health. However, no significant difference was found considering mean scores of nurses and ordinary people in Zabol on life expectancy.