Abstract: Hospitals are among the organizations that as the largest provider centers for health services are exposed to a lot of internal and external threats and their effective managing is due to the use of good strategic planning. However, the formulation and implementation of strategic planning in hospitals alone will not guarantee the success of hospital and as long as it is not in line with management plans of employee’s performance, it will have a little impact on the success of the hospital. The purpose of this study was to determine the relationship between formulation and implementation of strategic planning and performance management in hospitals staff of Tehran University of Medical Sciences. In this regard, two variables of strategic planning and performance management of staff (with six dimensions of: ability, improving work quality, reducing the amount of waste, job meaningfulness, accepting the results of work and creating organizational atmosphere for empowerment) were evaluated. The current study is a descriptive functional research and a questionnaire that its validity and reliability has been confirmed is used for data collection. The statistical population of study included 100 senior, middle and operational managers in three university hospitals of medical sciences which according to Krejcie and Morgan table, 79 of them were selected as samples through random sampling method. Based on the findings it is revealed that there is a significant relationship between the formulation and implementation of strategic planning and variables of ability, improving work quality, reducing the amount of waste and accepting the results of work and there is no significant relationship between the formulation and implementation of strategic planning and variables of job meaningfulness and creating organizational atmosphere for empowerment. Heads and administrators of hospitals should be aware of relationship between formulation and implementation of strategic plans and performance management in hospitals to achieve the desired results at the time of implementation of the strategic management process with forecasting and better managing the employee’s performance.