Authors : Ololade Zacchaeus S., Anuoluwa Iyadunni A and Ishaku Paul
Abstract: This research evaluates the extract of the leaf of Dialium guineense for its phytochemical and pharmacognostic potential. GC-MS, UV-Visible Spectrophotometer and other established biochemical methods assays were used for the study. GC-MS analysis showed the presence of 37 phytochemicals. The main component was: 4-O-methylmannose (49.0%). The β-carotene, lycopene, total carotenoid, chlorophyll a, b, total chlorophyll, TPC, TFC, TTC, TAA values were 0.20 mgg1, 0.10 mgg1, 12.68 mgg1, 4.40 mgg1, 4.70 mgg1, 7.80 mgg1, 2,668.17±0.01 μgmg1, 17.80±0.00 μgmg1, 152.65±0.01 μgmg1, 43.75±0.04, μgmg1, respectively while Galvinoxyl and DPPH antioxidant IC50 were 125.0 and 6.0 μgmL1, respectively. The TAC value was 279.49±0.01 μgmg1. The highest anti-arthritic value was 96.00%. The extract inhibited the growth of all the screener bacteria. These results showed that the leafcan be used in the treatment of various human and animals related aliment or diseases and more importantly in formulation food additives and preservative.
Ololade Zacchaeus S., Anuoluwa Iyadunni A and Ishaku Paul, 2021. Phytochemical, Pharmacognostic, Anti-Radical, Anti-Arthritic and Antibacterial Potential of the Leaf Extract of Dialium guineense. Research Journal of Applied Sciences, 16: 192-203.