Authors : Yuan Hu , Ting-Ting Hou , Hai-Liang Xin , Qiao-Yan Zhang , Han-Chen Zheng , Khalid Rahman and Lu-Ping Qin
Abstract: In most developing countries, 70-80% of the populations still resort to traditional medicine for their primary health care. This medicine utilizes medicinal plants which are traditionally taken as concoction and infusion. Ethanolic extracts of selected four Chinese medicinal plants in Vitex were tested for proliferative activity in ERá-positive MCF-7 human cell line using MTT assay. Vitex negundo showed the most estrogenic-like potent activity, which could be useful as a Hormone Replacement Therapy (HRP). In further investigation, the compounds with activities in Vitex negundo will be elucidated.
Yuan Hu , Ting-Ting Hou , Hai-Liang Xin , Qiao-Yan Zhang , Han-Chen Zheng , Khalid Rahman and Lu-Ping Qin , 2007. The Estrogenic-Like Activity of Four Chinese Medicinal Plants in Vitex. Research Journal of Biological Sciences, 2: 212-214.