Authors : S. Atashkhoyi and S. Negargar
Abstract: Shivering during spinal anesthesia in obstetric patients is one of the leading causes of discomfort for those patients. Tramadol is effective in the prevention and treatment of shivering after general anesthesia. The aim of this placebo-controlled study, was to investigate whether 1 mg kg-1 tramadol i.v. administered after spinal anesthesia would reduce the incidence and severity of shivering in patients undergoing cesarean section. In a randomized and double-blind clinical trial 70 healthy obstetric patients were scheduled for cesarean section under spinal anesthesia. Immediately, after spinal anesthesia 35 patients received 1 mg kg-1 tramadol in saline and 35 patients received saline normal. An anesthesiologist blind to the solution injected recorded incidence and intensity of shivering and pain and other parameters. The incidence of shivering was significantly lower in patients, who received tramadol than those who received placebo (28.57% v.s 65.71; p<0.0001). In the placebo group 26 (74.28%) patients had postoperative pain, compared to 4 (11.42%) in the study group (p<0.0001). There was no difference in the incidence of pharmacologic side effects. The results of this study revealed that tramadol 1 mg kg-1 i.v. is effective in prevention of shivering after spinal anesthesia for cesarean section.
S. Atashkhoyi and S. Negargar , 2008. Effect of Tramadol for Prevention of Shivering after Spinal Anesthesia for Cesarean Section. Research Journal of Biological Sciences, 3: 1365-1369.