Authors : Amir Hossein Ahmadi and Zeynab Ghazizadeh
Abstract: The purpose of this study is to evaluate the etiology of hyperbilirubinemia and the Prevalence of Glucose-6-phosphate Dehydrogenase (G6PD) deficiency in newborns who were admitted to Boali Hospital in Sari City during the period, 2004-2007. This prospective descriptive study has been conducted on 1018 icteric newborns. The dataset included: age, sex, total and direct bilirubin, hemoglobin, hematocryte, reticulocyte count, direct Coombs, G6PD level and the type of treatment. All data was analyzed by using statistical method. The prevalence of sepsis, ABO incompatibility, G6PD deficiency and Undetermined (Exaggerated physiological jaundice, prematurity, breast feeding jaundice, unknown) was 2.7% (27 neonates), 2.9% (30 neonates), 13.6% (138 neonates) and 80.1% (815 neonates), respectively. Those with severe jaundice and hyperbilirubinemia were hospitalized and treated with phototherapy or exchange transfusion. Despite a high prevalence of G6PD deficiency in our study, we recommend that G6PD deficiency tests be performed in all Iranian and Mediterranean icteric newborns.
Amir Hossein Ahmadi and Zeynab Ghazizadeh , 2008. Evaluation of Neonatal Hyperbilirubinemia at Mazandaran Province of Iran in 2004-2007: Prevalence of Glucose-6-Phosphate Dehydrogenase Deficiency. Research Journal of Biological Sciences, 3: 934-939.