Authors : M.R. Ebrahimpoor, Z. Khaksar and A. Noorafshan
Abstract: Antidiabetic effect of the alcoholic extract of Otostegia persica was investigated on 40 streptozotocin diabetic rats in four equal groups. Animals in first group did not receive any extract and were as a control for other groups. Rats in group II, III and IV received 200, 350 and 500 mg kg-1 daily administration of Otostegia persica oral extract, respectively for three weeks. Blood glucose level was estimated three times a day (8:00, 11:00 A.M and 5:30 P:M) in all groups. Statistical analysis of the results by t-test showed that the extract produced a dose-dependent decrease in the blood glucose level especially in fourth group (p<0.0001) in comparison with first group. Thus, study indicate that Otostegia persica has a strong antidiabetic action and can decrease the blood glucose level.
M.R. Ebrahimpoor, Z. Khaksar and A. Noorafshan, 2009. Antidiabetic Effect of Otostegia persica Oral Extract on Streptozotocin-Diabetic Rats. Research Journal of Biological Sciences, 4: 1227-1229.