Abstract: Tumors of the Central Nervous System (CNS), occur relatively frequently during the early years of life. They are the most common solid tumors of childhood and are second only to leukemia in overall cancer incidence and account for a high proportion of deaths. In different studied, performed in several countries, astrocytomas and other gliomas (combined) accounted for half of the CNS malignancies, followed by PNET/MB and ependymomas and then craniopharyngioma. We have undertaken a perspective study with 349 brain tumor patients, ranging from 0-14 years of age, throughout a 5 years period (1998-2003). Who were admitted in Tabriz Koodakan Hospital or were diagnosed in Tabriz Hafez CT scan center, during radiological evolutions by CT. Craniopharyngioma was the most common type of tumors among patients studied in the series and astriocytomas was second and medulloblastoma was third common type. The male/female proportion of patients in total brain tumors according to the results is 1.56 and it is similar to earlier studies. About medulloblastoma and ependymomas, male/female proportion of patients in study is <1 (0.88, 0.7), but in earlier series it seems to be >1 (about 1.4). Age-related distribution of brain tumors in children under the age 14 was similar to that of other series to some extent. Also, since the causes and risk factors of CNS cancers remain largely undetermined, we could not reach a significant relationship between the tumors and location of life of patients. Hope that the results make a useful for the future studies in this field and differences obtained in this study with results of other series can help us more and more in management and treatment strategies if brain tumors in children of the population.
Zinat Miabi and Omid Mashrabi, 2009. Pediatric Brain Tumor. Research Journal of Biological Sciences, 4: 647-650.