Abstract: The skin is the body’s largest organ. Melanoma and NMSC are now the most common types of cancer in white populations and both show an increasing incidence rate worldwide. The goal of this study was answering questions about skin malignancies epidemiologic pattern in Semnan. This study carried out in Semnan, Iran, from 1999-2007. Results of data from Semnan compared with meta-analysis results. Frequency of skin malignancies was 18.40%. Totally, the skin cancers were most prevalent malignancy. The most prevalent skin malignancies were BCC 65.1, SCC 28.5 and melanoma 1.07%. Male sex ratio was 61.87% for all cases, 56.9% for BCC and 72.2% for SCC cases (p = 0.02). Mean age was 64.92 years for all skin malignancies, 65.74 in males and 63.74 years for females (p>0.05). This was 63.42 and 68.25 years for BCC and SCC, respectively (p = 0.026). The most prevalent sites were nose or other parts of face with 40.21% and scalp and neck with 22.78%. The most prevalent site for BCC and SCC was nose or other parts of face to with 47.5 and 26.6%, respectively (p = 0.002). Present results showed relatively constant trends by time for incidence of skin malignancies, including BCC and SCC and for sex and age. Epidemiologic pattern of skin cancers in Semnan was roughly comparable with the corresponding indexes in world and Iran especially for NMSC (BCC and SCC) comparing with other parts of Iran and Middle Asia, but the incidence of melanoma was lower.
Semnani Vahid, A. Toussy Jafar, Soltany Setareh and Toghraie Mirmohammad, 2009. Epidemiologic Pattern of Skin Malignancies in Semnan, Iran Between 1999 and 2007 and Comparing it with Meta-Analysis of Published Papers in World Between 2000 and 2008. Research Journal of Biological Sciences, 4: 743-751.