Authors : A. Hassanpour, R. Pakravani and S. Safarmashaei
Abstract: Theilleriosis is one of the common protozoan disease in cows that experimental figures of this disease has great help in diagnosis and treatment. This study aimed to evaluate serum concentrations of sialic acid (total sialic acid and lipid compound sialic acid and protein compound sialic acid) as markers of inflammation in infected cattle. In the large anilmal clinic of Islamic Azad University, Veterinary Faculty and some dairy cattle farm around Tabriz, 37 infected cows to Theilleriosis were determinded based on clinical and experimental signs. They obtained blood samples from the jugular vein and serum was isolated. Total 35 cows were taken as control samples. Serum levels of these parameters were measured using Sydow and Katpodis method. Mean values of serum sialic acid, lipid compound sialic acid and proteins compound sialic acid in infected cattle to Theilleriosis were 3.26±0.13, 1.10±0.070, 0.91±0.056 mmol L-1 and in healty cows were 1.96±0.12, 0.68±0.064, 0.74±0.061 mmol L-1, respectively that differences between the two groups in all three cases was significant (p = 0.000, p = 0.000, p = 0.046, respectively). It was found that patients with elevated serum levels of total serum sialic acid, total amount of lipid compound sialic acid and proteins compound sialic acid are increased. But there was no significant correlation between them (r = 0.136, 0.064, respectively). The final result is that increase of sialic acid serum concentration in infected cows to Theilleriosis is mark of inflammation trend and measuring this parameter in experimental verifying of Theilleriosis disease can be useful.
A. Hassanpour, R. Pakravani and S. Safarmashaei, 2011. Evaluation of Serum Sialic Acid in Cows with Theilleriosis. Research Journal of Biological Sciences, 6: 237-239.