Authors : T.O. Ikpesu and L.I.N. Ezemonye
Abstract: The correlation between endosulfan accumulation and tissue damages was examined on induced Oreochromis niloticus. The organization for economic cooperation and development No. 407 recommended static renewal bioassay was employed during the test. The test fish were exposed to sub-lethal concentrations separately for a period of 7, 14, 21 and 28 days. At the end, of each exposure period the liver tissues were isolated and analyzed using high performance liquid chromatography for bioaccumulation study while alterations observed in exposed fish were determined in the laboratory by light microscopy using standard technique of haematoxylin and eosin staining. No mortalities occurred in any group during the test. The severity of the histological alterations observed in the liver of the treated fish, reflects the concentrations of the toxicant, level of depuration and exposure durations. An indication that that the regulating mechanisms of the liver has been overwhelmed resulting in the structural damages. The findings showed that the body could be liberated of contaminants after longer exposure period, however the effects on the body’s tissues remain lethal.
T.O. Ikpesu and L.I.N. Ezemonye, 2013. The Significant of Poisson Load on Tissue Alteration with Reference to Histopathological Changes in Induced Oreochromis niloticus. Research Journal of Biological Sciences, 8: 179-186.