Abstract: The study examined Library and Information Science lecturers’ attitude towards open access scholarly publications in Southern Nigeria. Consequently, three objectives were set out for the study. The descriptive survey design was employed and the questionnaire entitled Attitude towards Open Access to Scholarly Publications Questionnaire (AOASPQ) was administered on the entire population of 141 LIS lecturers from which 114 responses were successfully collected. The data collected were analyzed using frequency counts, percentages, mean and regression analysis. The study revealed that though the level of usage of open access publications by both senior and junior LIS lecturers is high, usage by junior lecturers are a bit higher. That notwithstanding, both cadre of lecturers exhibit similar positive attitude towards open access publications and this situation was found to account for 20.20% of their tendency to use open access publications. The study recommends that management should equip schools with the enabling infrastructure and that academic reward systems should be designed to encourage open access publications. Tenure and promotion review committee members should have a change of attitude in evaluating publications in open access.