Abstract: Sheibani kings in the late 16th century and early 17th century, unified and sovereign state able to make them a tribal leader Muhammad Sheibani in Fararudi Tuman area who have migrated to Transoxiana and Sheibani Khan was able to unite the nomadic tribes invaded initiated against Timurid authority in Transoxiana and was able to take in the short term and Timurid successor states in the region and to form Khanan Uzbek Bukhara and Samarkand as Sheibanis and then he thought that the government was established in Transoxiana invasion of Safavid realm in Khorasan and was successful in limited time to seize the points of Khorasan. It was faced with defending the rule of the Safavid their various battles between the two groups was formed, the one who had won the battle Safavid followed the death of Muhammad Shaybani Uzbeks, returning to Transoxiana after Muhammad Shaybani Obaidullah Khan succeeded him thought Khorasan and avenge the invasion of Muhammad Shaybani was always thinking he is observing the battle Ghjdvan he was able to defeat the Safavid and Uzbeks won a great victory that was very satisfactory durability Open results found for Uzbek bitter battles against the Safavid. It Ubaidullah was wounded later died due to injuries and part of the history of Transoxiana another way overstretched and it was the arrival of Abdul Aziz Khan and his 6 years reign this time things were a little slow and look for weaknesses in the system of government he set aside great and Abdullah Khan sat in his place during his rule, he would have seized the whole of Transoxiana and cut into large civil works, he had even managed to cross the Mashhad seized power and courage based on a large Uzbek Khan, he said, it should be noted that generally relate corner of Central Asian history at Sheibani is Khanan been investigated and the less will be considered by researchers interested in the history of this area.