Abstract: The aim of this study was to analyze the inequality of opportunities for the metropolitan regions of the Brazilian capitals in 2010. Inequality of opportunity is considered a situation in which personal characteristics of an individual or family influence access to services such as clean water, education, sanitation and garbage collection. We estimated the Human Opportunity Index (HOI) for the capitals of Brazil and their neighborhoods. We also identified the main factors correlated with inequality of opportunity through Shapley’s Model for neighborhoods of the cities with the best and worst HOI ratings. The educational and sanitation dimensions require special attention in social policies, since both combine low availability of service with high in equality of access, especially in the North-Northeast.