Abstract: The objective of the study is to investigate the influence of social media and digital participation in politics of the first time eligible voters in 2019, university students in Thailand. The 29 items of a questionnaire was developed from literature review and tested validity (KMO = 0.899, 0.937) and reliability (Alpha = 0.89, 0.92) and collected 400 respondents of the university students before the election in March, 2019 in Thailand. The statistical analysis are variance analysis and Stepwise Multi Regression analysis. Facebook, Twitter and Instagram are social media usage in this study. The results revealed that the sub-variables of social media usage such as time in using social media (Sm4) and sharing like (Sm12) and sub-variables of political participation in terms of supporting activity (Sa), voting and following information (Ei), predicted significantly at 0.05, on digital participation in politics. Moreover, these 4 sub-variables also demonstrated moderately the coefficient at R² = 0.43, 0.36, 0.009 and 0.023, respectively, to digital participation in politics. Consequently, the utilizing of Facebook and Twitter for the benefits of political participation should be related mainly to solving the civic problems.