References

Alexopoulou, O., J. Jamart, D. Maiter, M.P. Hermans, R. de Hertough, de Nayer and M. Buysschaert, 2001. Erectile dysfunction and lower androgenicity in type 1 diabetic patients. Diabetes Metab., 27: 329-336.
PubMed  |  

Anderson, J.E. and J.A. Thliveris, 1986. Testicular histology in streptozotocin induced diabetes. Anat. Rec., 214: 378-382.
PubMed  |  

Anderson, J.E. and J.A. Thliveris, 1987. Morphometry and cytochemistry of Leydig cells in experimental diabetes. Am. J. Anat., 180: 41-48.
PubMed  |  

Aslan, M., O.D. Deliorman, N. Orhan, E. Sezik and E. Yesilada, 2007. In vivo antidiabetic and antioxidant potential of Helichrysum plicatum sp. plicatum capitulums in streptozotocin-induced-diabetic rats. J. Ethnopharmacol., 109: 54-59.
PubMed  |  

Baytop, T., 1999. Turkiyede Bitkiler Ile Tedavi. Nobel Tip Kitabevleri, Istanbul, pp: 309-310.

Bucholtz, D.C., A. Chiesa, W.N. Pappano, S. Nagatani, H. Tsukamura, K.I. Maeda and D.L. Foster, 2000. Regulation of pulsatile luteinizing hormone secretion by insulin in the diabetic male lamb. Biol. Reprod., 62: 1248-1255.
PubMed  |  

Bukhari, I.A., R.A. Khan, A.U. Gilani, A.J. Shah, J. Hussain and V.U. Ahmad, 2007. The analgesic, anti-inflammatory and calcium antagonist potential of Tanacetum artemisioides. Arch Pharm. Res., 30: 303-312.
CrossRef  |  PubMed  |  Direct Link  |  

Cai, L., S. Chen, T. Evans, D.X. Deng, K. Mukherjee and S. Chakrabarti, 2000. Apoptotic germ-cell death and testicular damage in experimental diabetes: Prevention by endothelin antagonism. Urol. Res., 28: 342-347.
CrossRef  |  PubMed  |  Direct Link  |  

Cameron, D.F., F.T. Murray and D.D. Drylie, 1985. Interstitial compartment pathology and spermatogenic disruption in testes from impotent diabetic men. Anat. Rec., 213: 53-62.
PubMed  |  

Carlson, B.M., 2004. Human Embryology and Developmental Biology. 3rd Edn., Elsevier, London, ISBN: 0-323-03649-x.

Cernochova, D. and V. Kamarad, 1992. Toxic effect of lead of mice testicles after its administration with drinking water. Acta Univ. Palacki Olomuc. Fac. Med., 133: 9-13.
PubMed  |  

Chen, H., R. Feng, Y. Guo, L. Sun and J. Jiang, 2001. Hypoglycemic effects of aqueous extract of Rhizoma polygonatiodorati in mice and rats. J. Ethnopharmacol., 74: 225-229.
PubMed  |  

Crawford, J.M. and R.S. Cotran, 1999. The Pancreas. In: Robbins Pathologic Basis of Disease, Cotran, R.S., V. Kumar and T. Collins (Eds.). WB Saunders Company, USA., pp: 913-920.

De Tejada, S.I., I. Goldstein, K. Azadzoi, R.J. Krane and R.A. Cohen, 1989. Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence. New Engl. J. Med., 320: 1025-1030.
PubMed  |  Direct Link  |  

Guneli, E., K. Tugyan, H. Ozturk, M. Gumustekin, S. Cilaker and N. Uysal, 2008. Effect of melatonin on testicular damage in streptozotocin-induced diabetes rats. Eur. Surg. Res., 40: 354-360.
PubMed  |  

Hassan, A.A., M.M. Hassouna, T. Taketo, C. Gagnon and M.M. Elhilali, 1993. The effect of diabetes on sexual behavior and reproductive tract function in male rats. J. Urol., 149: 148-154.
CrossRef  |  PubMed  |  Direct Link  |  

Kaya, M., 1986. Sertoli cells and various types of multinucleates in rat seminiferous tubules following temporary ligation of the testicular artery. J. Anat., 144: 15-29.
PubMed  |  

Leon, M.D., V.A. Chiauzzi, J.C. Calvo, E.H. Charreau and H.E. Chemes, 1987. Acute hCG administration induces seminiferous tubule damage in the adult rat. Acta Physiol. Pharmacol. Latinoam, 37: 277-277.
PubMed  |  

McCulloch, D.K., I.W. Campbel, F.C. Wu, R.J. Prescott and B.F. Clarke, 1980. The prevalence of diabetic impotence. Diabetologia, 18: 279-283.
PubMed  |  

Onturk, H. and H. Ozbek, 2007. Carried out of experimental diabetes and the measurement of glycemic activity. Genel Tip Derg., 17: 231-236.

Ozbek, H., 2002. Investigation of the level of the lethal dose 50 and the hypoglycemic effect of Foeniculum vulgare Mill. Fruit essential oil extract in healthy and diabetic mice. Van Tip Derg., 9: 98-103.

Ozbek, H., F. Ozgokce, E. Ceylan, A. Tas and M. Tuncturk, 2002. Investigation of the hypoglycemic effects of Secale cereale L. fruit decoction extract in healthy and diabetic mice. Van Tip Derg., 9: 73-77.

Ozturk, F., M. Gul, M. Agkadir and M. Yagmurca, 2002. Histological alterations of rat testes in experimental diabetes. T Klin. Tip Bilimleri, 22: 22-178.

Richburg, J.H., 2000. The relevance of spontaneous and chemically-induced alterations in testicular germ cell apoptosis to toxicology. Toxicol. Lett., 112: 79-86.
PubMed  |  

Sanguinetti, R.E., K. Ogawa, M. Kurohmaru and I. Hayashi, 2004. Ultrastructural changes in mouse Leydig cells after streptozotocin administration. Exp. Anim., 44: 71-73.
Direct Link  |  

Sasagawa, I., T. Nakada, Y. Kubota, M. Ishigooka, K. Uchida and K. Doi, 1995. In vivo 31P magnetic resonance spectroscopy for evaluation of testicular function in cryptorchid rats. J. Urol., 154: 1557-1559.
PubMed  |  

Sinha-Hikim, A.P. and R.S. Swerdloff, 1999. Hormonal and genetic control of germ cell apoptosis in the testis. Rev. Reprod., 4: 38-47.
CrossRef  |  

Smirnov, V.V., N.E. Preobrazhenskaia and I.D. Kalashnikov, 1982. Antibacterial properties of Helichrysum plicatum DC. Mikrobiol. Zhurnal, 44: 71-72.
PubMed  |  Direct Link  |  

Steger, R.W. and M.B. Rabe, 1997. The effect of diabetes mellitus on endocrine and reproductive function. Proc. Soc. Exp. Biol. Med., 214: 1-11.
PubMed  |  

Steger, R.W., 1990. Testosterone replacement fails to reverse the adverse effects of streptozotocin-induced diabetes on sexual behavior in the male rat. Pharmacol. Biochem. Behav., 35: 577-582.
PubMed  |  

Stellato, R.K., H.A. Feldman, O. Hamdy, E.S. Horton and J.B. McKinlay, 2000. Testosterone, sex hormone-binding globulin and the development of type 2 diabetes in middle-aged man. Diabetes Care, 23: 490-494.
PubMed  |  

Sudha, S., G. Valli, P.M. Julie, J. Arunakaran, P. Govindarajulu and K. Balasubramanian, 2000. Influence of streptozotocin-induced diabetes and insulin treatment on the pituitary-testicular axis during sexual maturation in rats. Exp. Clin. Endocrinol. Diabetes, 108: 14-20.
PubMed  |  

Tabanca, N., F. Demirci, B. Demirci, D.E. Wedge and K.H. Baser, 2007. Composition, enantiomeric distribution and antimicrobial activity of Tanacetum argenteum subsp. flabellifolium essential oil. J. Pharm. Biomed. Anal., 45: 714-719.
CrossRef  |  PubMed  |  Direct Link  |  

Thresher, J.S., D.A. Podolin, Y. Wei, R.S. Mazzeo and M.J. Pagliassotti, 2000. Comparison of the effects of sucrose and fructose on insulin action and glucose tolerance. Am. J. Physiol. Regul. Integr. Comp. Physiol., 279: R1334-R1340.
PubMed  |  

Torgersen, H.M., E. Rovan, M. Steiner, J. Frick and H. Adam, 1982. BCG induced orchitis: Structural changes during the degeneration of seminiferous tubules of rats and rabbits. Urol. Res., 10: 97-104.
PubMed  |  

Utkan, T., M.K. Yildirim, S. Yildirim and Y. Sarioglu, 2001. Effects of the specific phosphodiesterase inhibitors on alloxan-induced diabetic rabbit cavernous tissue in vitro. Int. J. Impotence Res., 13: 243-244.
PubMed  |  

Vernet, D., L. Cai, H. Garban, F.T. Murray, J. Rajfer and N.F. Gonzalez-Cadavid, 1995. Reduction of penile nitric oxide synthase in dp (type 1) and BBZ/WOR (type II) rats diabetic BB/WOR with erectile dysfunction. Endocrinology, 136: 5709-5709.

Wright, J.R., A.J. Yates, H.M. Sharma, C. Shim, R.L. Tigner and P. Thibert, 1982. Testicular atrophy in the spontaneously diabetic BB Wistar rat. Am. J. Pathol., 108: 72-79.
PubMed  |