References

Cheng, J.B., M.A. Levine, N.H. Bell, D.J. Mangelsdorf and D.W. Russell, 2004. Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase. Proc. Natl. Acad. Sci. USA, 101: 7711-7715.
Direct Link  |  

Elkum, N., F. Alkayal, F. Noronha, M.M. Ali and M. Melhem et al., 2014. Vitamin D insufficiency in Arabs and South Asians positively associates with polymorphisms in GC and CYP2R1 genes. PloS One, Vol. 9, 10.1371/journal.pone.0113102

Leung, T.F., S.S. Wang, M.F. Tang, A.P.S. Kong and H.Y. Sy et al., 2015. Childhood asthma and spirometric indices are associated with polymorphic markers of two vitamin D 25-hydroxylase genes. Pediatr. Allergy Immunol., 26: 375-382.
CrossRef  |  PubMed  |  Direct Link  |  

Li, Y.C., Y. Chen and J. Du, 2015. Critical roles of intestinal epithelial vitamin D receptor signaling in controlling gut mucosal inflammation. J. Steroid Biochem. Mol. Biol., 148: 179-183.
CrossRef  |  PubMed  |  Direct Link  |  

Nissen, J., U. Vogel, H.G. Ravn, E.W. Andersen and K.H. Madsen et al., 2015. Common variants in CYP2R1 and GC genes are both determinants of serum 25-hydroxyvitamin D concentrations after UVB irradiation and after consumption of vitamin D3-fortified bread and milk during winter in Denmark. Am. J. Clin. Nutr., 101: 218-227.
CrossRef  |  Direct Link  |  

Park, J.M., C.Y. Park and S.N. Han, 2015. High fat diet-induced obesity alters vitamin D metabolizing enzyme expression in mice. BioFactors, 41: 175-182.
CrossRef  |  PubMed  |  Direct Link  |  

Shui, I.M., A.M. Mondul, S. Lindstrom, K.K. Tsilidis and R.C. Travis et al., 2015. Circulating vitamin D, vitamin D-related genetic variation and risk of fatal prostate cancer in the national cancer institute breast and prostate cancer cohort consortium. Cancer, 121: 1949-1956.
CrossRef  |  PubMed  |  Direct Link  |  

Slater, N.A., M.L. Rager, D.E. Havrda and A.F. Harralson, 2015. Genetic variation in CYP2R1 and GC genes associated with vitamin D deficiency status. J. Pharm. Pract., 1: 1-6.
CrossRef  |  Direct Link  |  

Stroud, M.L., S. Stilgoe, V.E. Stott, O. Alhabian and K. Salman, 2008. Vitamin D: A review. Aust. Family Physician, 37: 1002-1005.
Direct Link  |  

Thacher, T.D., P.R. Fischer, R.J. Singh, J. Roizen and M.A. Levine, 2015. CYP2R1 mutations impair generation of 25-hydroxyvitamin D and cause an atypical form of vitamin D deficiency. J. Clin. Endocrinol. Metab., 100: E1005-E1013.
CrossRef  |  PubMed  |  Direct Link  |